A downloadable game for Windows and macOS

LigandQuest is a physics-based educational game designed to teach core pharmacology concepts to anyone. Fling chemical messengers around with the mouse and cause changes in the patient's body. The game has 11 prebuilt levels that cover basic pharmacological concepts as well as an incredibly powerful level editor, which allows players to create levels and demonstrate knowledge. Levels are saved as files that are easily shareable.

This game was developed by Ryan O'Hara and Andy Mechalakos and funded via the QUIP-RS grant program at Quinnipiac University.


LigandQuest_Windows_ver1.1.zip 15 MB
LigandQuest_Mac_ver1.1.zip 20 MB

Install instructions

Unzip the file and put its contents somewhere where you can find them. The game file is the one with the LigandQuest icon. Open that.


  • On Mac, you'll need to hold control when you open the app for the first time, then choose Open. Macs have security that won't let you open files that didn't come from the app store unless you do this.
  • On Windows, the game and the "LigandQuest_Data" folder MUST be in the same place, or else the game won't run.